Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrated.
"The MEL gene: a new member of mont tremblant rabais derniere minute the RAB/YPT class of RAS-related genes"."Isoprenylation of Rab proteins possessing a C-terminal CaaX motif".The Journal of Cell Biology.The Journal of Biological Chemistry.Hattula K, concours secrétaire administratif 2017 forum Furuhjelm J, Arffman A, Peränen J (Sep 2002).Hattula K, Peränen J (2000).Cubase FX 4:28 0:59,."Prenylation of Rab8 promo outils lidl GTPase by type I and type II geranylgeranyl transferases"."In its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase".Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (Mar 2002).The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins.
Zico fl8 from lesson 2:04.
Linder MD, Uronen RL, Hölttä-Vuori M, van der Sluijs P, Peränen J, Ikonen E (Jan 2007).
"Physical mapping of human myosin-IXB (MYO9B the human orthologue of the rat myosin myr 5, to chromosome 19p13.1".Shisheva A, Chinni SR, DeMarco C (Sep 1999).However, this protein contains a C-terminal caax motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins."Confirmation and refinement of the localisation of the c-MEL locus on chromosome 19 by physical and genetic mapping".Fukuda M (Apr 2003).A b "Entrez Gene: RAB8A RAB8A, member RAS oncogene family".The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane.